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https://www.sciencedirect.com/science/article/pii/S1064748112620764
Background. Patients with bipolar disorder are at risk to develop cognitive decline in the course of their illness. This may affect their ability to monitor and detect their own cCited by: 17
https://www.researchgate.net/publication/51586115_Self-Reported_Cognitive_Complaints_in_Elderly_Bipolar_Patients
Elderly bipolar patients had no more subjective cognitive complaints than comparison subjects, whereas they showed less cognitive functioning in several domains.
https://research.vu.nl/en/publications/self-reported-cognitive-complaints-in-elderly-bipolar-patients
RESULTS: Elderly bipolar patients had no more subjective cognitive complaints than comparison subjects, whereas they showed less cognitive functioning in several domains. Having few subjective cognitive complaints was associated with poorer attentional and executive functioning.Cited by: 17
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876097/
May 17, 2016 · One of the studies comparing comorbidities in bipolar versus non-bipolar subjects found a high prevalence of viral hepatitis and Parkinson’s disease among older bipolar patients.15 A recent study reported that most of the elderly bipolar patients did not present psychiatric comorbidities, and those who did were mainly patients with early-onset BD.Cited by: 10
https://www.sciencedirect.com/science/article/pii/S0165032714007216
The Chinese version of the COBRA is a brief 16-item, self-reported, one-dimension instrument, detecting the main cognitive deficits experienced by bipolar patients such as executive function, processing speed, working memory, verbal learning and memory, attention/concentration and mental tracking.Cited by: 8
https://www.nia.nih.gov/health/assessing-cognitive-impairment-older-patients
As a primary care practice, you and your staff are often the first to address a patient’s complaints—or a family’s concerns—about memory loss or possible dementia. (1,2) This quick guide provides information about assessing cognitive impairment in older adults.
https://link.springer.com/chapter/10.1007/978-3-319-48912-4_2
Jan 06, 2017 · The clinical assessment of the older adult with bipolar disorder requires careful consideration of aging-related factors such as increased risk of dementia, medical and psychiatric comorbidities, and the psychological sequelae of cumulative medical burden, cognitive decline, and functional impairment.Author: Annemiek Dols, Peijun Chen, Rayan K. Al Jurdi, Martha X Sajatovic
https://www.everydayhealth.com/bipolar-disorder/bipolar-disorder-in-seniors.aspx
Ongoing research is comparing lithium to antiseizure medications in older bipolar patients in order to determine which type of drug has the greatest benefit with the least risk of side effects. Talk therapy can also be a valuable addition to bipolar treatment for older adults.
https://www.consumerhealthdigest.com/brain-health/cognitive-issues-elderly.html
Cognitive impairment in the elderly has a number of causes ranging from medication side effects to depression and neurodegenerative disorders. There is no consensus regarding the age of onset of cognitive decline.
https://www.researchgate.net/publication/325548504_THE_PREVALENCE_OF_MASKED_HYPERTENSION_AMONG_OLDER_PATIENTS_WITH_COGNITIVE_COMPLAINTS
Results from the M4 trial will provide evidence of combined multiple-modality and cognitive training among older adults with self-reported cognitive complaints on cognitive, mobility-related and ...
https://www.medscape.com/viewarticle/883972
Oct 15, 2019 · About 5% of new bipolar cases occur in this older age group. In general, when you are faced with a patient like this, your assumption should be that this is a so-called secondary mania—not from bipolar disorder the genetic illness, per se, but one that is more likely to have a medical cause.
https://www.healthyplace.com/bipolar-disorder/articles/management-of-mania-in-the-elderly
Elderly bipolar affective disorder patients have higher risks for tardive dyskinesia. Atypical medications have lower risk rates of EPS. Olanzapine and Risperidone behave like high potency typical anti-psychotic medication while seroquel is more like a low potency typical anti-psychotic.
https://www.bipolar-lives.com/bipolar-disorder-and-seniors.html
Researchers are also discovering that bipolar disorder doesn’t “disappear” as adults grow older. In fact, studies show that the symptoms often worsen over time though this might also be due to misdiagnoses. The care of seniors with bipolar disorder often depends on relatives, and it can be a difficult task.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304584/
Assessment of Cognitive Dysfunction in Major Depressive Disorder. The bias toward negative cognitive schemes found in MDD is likely to contribute, at least in part, to the high percentage of patients reporting subjective cognitive complaints during depressive episodes.Cited by: 141
https://www.researchgate.net/publication/7672554_Do_Cognitive_Complaints_in_Euthymic_Bipolar_Patients_Reflect_Objective_Cognitive_Impairment
Patients with bipolar disorder in partial or full remission (n=84) and healthy controls (n=68) were assessed with the Screen for Cognitive Impairment in Psychiatry (SCIP), Cognitive Complaints in ...
https://onlinelibrary.wiley.com/doi/full/10.1111/bdi.12595
Key recommendations are that clinicians: (I) formally screen cognition in partially or fully remitted patients whenever possible, (II) use brief, easy‐to‐administer tools such as the Screen for Cognitive Impairment in Psychiatry and Cognitive Complaints in Bipolar Disorder Rating Assessment, and (III) evaluate the impact of medication and comorbidity, refer patients for comprehensive neuropsychological evaluation when …
https://www.researchgate.net/publication/8172058_Effect_of_Lamotrigine_on_Cognitive_Complaints_in_Patients_With_Bipolar_I_Disorder
Interviews and assessment of the cognitive function were made in the euthymic phase of the disorder. In all, 118 unipolar patients, 28 bipolar patients and 58 controls were included. Analyses were adjusted for differences in the level of education and for subclinical depressive and anxiety symptoms.
https://www.dovepress.com/clinical-features-comorbidity-and-cognitive-impairment-in-elderly-bipo-peer-reviewed-fulltext-article-NDT
Nov 19, 2015 · Cognitive abilities of older bipolar patients (BD-I) in euthymic state have also been compared with patients with schizophrenia in the same age range. 26 Strikingly limited differences in cognitive performance between the community-living patients with schizophrenia and the bipolar patients were found. However, both groups were impaired ...
https://www.ncbi.nlm.nih.gov/pubmed/15554760
RESULTS: Bipolar patients in both trials had significant cognitive impairment; however, it was much greater in index episode depressed bipolar patients compared with index episode manic patients. In both studies, substitution of lamotrigine for other psychotropic medications significantly improved the mean scores from baseline to the end of the ...
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